Absence of YhdP, TamB, and YdbH leads to defects in glycerophospholipid transport and cell morphology in Gram-negative bacteriaYHDP, TAMB 및 YDBH의 부재는 그람 음성 박테리아에서 글리세로 포스 포스 폴리티드 수송 및 세포 형태의 결함으로 이어진다Research Article Published on 2022-02-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence accumulate adjust anterograde antibiotic Antibiotic resistance asymmetric Bacterial balance biosynthetic biosynthetic pathways Cell cell envelope cell lysis changes in characterized component contribute Critical Defense effective foundation gram Gram-negative bacteria homeostasis homologues inner leaflet leads lipopolysaccharide LPS maintain maintaining membrane membrane vesicles morphology mutant offer outer membrane overexpression pathway phenotype Phenotypes Protein provide reducing rescued restored sensitivity shedding the cell Therapies Threats translocated Transport understanding vesicles viability [DOI] 10.1371/journal.pgen.1010096 PMC 바로가기 [Article Type] Research Article
An Intranasal OMV-Based Vaccine Induces High Mucosal and Systemic Protecting Immunity Against a SARS-CoV-2 Infection비강내 OMV 기반 백신은 SARS-CoV-2 감염에 대한 높은 점막 및 전신 보호 면역을 유도합니다Immunology Published on 2021-12-172022-09-11 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, 치료기술, 치료제, [키워드] administer Administered administration Against antibody booster vaccination booster vaccinations candidate vaccine CHO cells clinical development clinical testing control group control groups COVID-19 COVID-19 vaccine COVID-19 vaccines Cramp D614G effective eight greater hamster hamsters Histopathology IgA IgG IgG response immune protection immune response Immunity Immunoglobulin Immunoglobulin G inactivated induce intramuscular intramuscular vaccination intramuscularly intranasal intranasally lesion Local lung Lungs majority membrane vesicles mice mRNA mucosal mucosal immunity Neisseria Neisseria meningitidis Neutralizing antibodies nose offer OMV outer membrane outer membrane vesicle pandemic peptide peptide sequence practicality produced proline Protecting reduced Registered required SARS-CoV-2 SARS-CoV-2 pandemic second vaccination sequence serum Spike protein subunit Subunit vaccine Support systemic the SARS-CoV-2 Transmission vaccination Vaccinations Vaccine variants Vesicle Viral viral entry viral replication Viral vector weight loss [DOI] 10.3389/fimmu.2021.781280 PMC 바로가기 [Article Type] Immunology
Characterization of Feces-Derived Bacterial Membrane Vesicles and the Impact of Their Origin on the Inflammatory ResponseOriginal Research Published on 2021-05-072023-08-30 Journal: Frontiers in Cellular and Infection Microbiology [Category] E형 간염, [키워드] bacterial phyla bead-based flow cytometer Inflammatory response intestinal microbes membrane vesicles [DOI] 10.3389/fcimb.2021.667987 PMC 바로가기 [Article Type] Original Research
Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation말단 부속기 단백질 CEP164에 대한 조건부 녹아웃 마우스는 기도 다중섬모 세포 분화에서 필수적인 역할을 밝힙니다Research Article Published on 2017-12-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence addition affecting airway airways arising Arl13b Asthma basal body binding Brain Cby1 Cell cell differentiation cells CEP164 cerebrospinal fluid characterized chronic obstructive ciliary ciliary dyskinesia circulation clearance component Control COPD Critical cystic fibrosis develop differentiation disease disorder distal docking dysfunction dyskinesia Evidence female reproductive tract fiber fibrosis fluids Genetic genetic disease GTPase Health human biology hydrocephalus implicated Infection infertility knockout mice lack lining male male infertility membrane vesicle membrane vesicles mice modulate molecular mechanism molecular mechanisms Mucociliary clearance Mucus multicilia oviduct Patient Perturbation physiological primary ciliary dyskinesia primary culture Protein Proteins provide recruitment regulate Regulation respiratory respiratory diseases selective Structure Symptom Testis tissue tracheal Transport unique Vesicle while [DOI] 10.1371/journal.pgen.1007128 PMC 바로가기 [Article Type] Research Article